PXD057053-1

PXD057053 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	proteome sequencing for the colon tissues of mice with ckmt1 knockout
Description	We here performed a proteomics study on the colon tissues of ckmt1 KOIEC or. WT (flox+/+) mice after DSS treatment for 8 days (n=3). KOIEC mice (Ckmt1flox/flox, Vil-Cre) means mice with intestinal epithelial conditional knockout (C57BL/6J). Cre-negative Ckmt1 flox/flox littermates were used as controls. Group 1: DSSCKO (Ckmt1flox/flox, Vil-Cre) Group 2: DSSflox (Cre-negative Ckmt1 flox/flox littermates)
HostingRepository	PRIDE
AnnounceDate	2025-05-07
AnnouncementXML	Submission_2025-05-07_04:00:06.006.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhijie Wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-22 04:00:04	ID requested
⏵ 1	2025-05-07 04:00:06	announced

Publication List

10.1038/s41419-025-07504-4;
Wang Z, Wu H, Chang X, Song Y, Chen Y, Yan Z, Gu L, Pang R, Xia T, He Z, Li Z, Wang S, Bai Y, CKMT1 deficiency contributes to mitochondrial dysfunction and promotes intestinal epithelial cell apoptosis via reverse electron transfer-derived ROS in colitis. Cell Death Dis, 16(1):177(2025) [pubmed]

10.1038/s41419-025-07504-4;

Wang Z, Wu H, Chang X, Song Y, Chen Y, Yan Z, Gu L, Pang R, Xia T, He Z, Li Z, Wang S, Bai Y, CKMT1 deficiency contributes to mitochondrial dysfunction and promotes intestinal epithelial cell apoptosis via reverse electron transfer-derived ROS in colitis. Cell Death Dis, 16(1):177(2025) [pubmed]

Keyword List

submitter keyword: proteome sequencing
IBD
DSS-induced model
mice
colon

submitter keyword: proteome sequencing

IBD

DSS-induced model

mice

colon

Contact List

Zhijie Wang
contact affiliation	Changhai Hospital, Naval Medical University, Shanghai, 200433, China.
contact email	woshiwangzhijie@126.com
lab head
Zhijie Wang
contact affiliation	Changhai Hospital
contact email	woshiwangzhijie@126.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057053
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD057053

PRIDE project URI

Repository Record List

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