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PXD056926-1

PXD056926 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFusing Engineered Bacterial Strains with NIR-II AIEgen for Multimodal Image-guided Phototherapy and Immunotherapy
Descriptionwe present an aggregation-induced emission (AIE) - bacteria hybrid bionic robot to address the above issues. This bionic robot is composed of a multifunctional AIE molecule, INX-2 and Escherichia coli Nissle 1917 (EcN), i.e. EcN@INX-2. The robot is characterized by NIR-II fluorescence emission with efficient photodynamic and photothermal effects and tumor targeting, which was realized by INX-2 and EcN respectively, EcN@INX-2 achieved in vivo multimodal imaging and therapy of the tumors through multiple mechanisms including the activation of anti-tumor immunity, photodynamic and photothermal therapy in CT26 tumor-bearing female mice.
HostingRepositoryiProX
AnnounceDate2024-10-18
AnnouncementXMLSubmission_2024-10-17_20:23:41.869.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLiwei Zhu
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-10-17 20:23:29ID requested
12024-10-17 20:23:42announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Aggregation-induced emission, Bacteria, Bionic Robot, Phototheranostics, Immunotherapy
Contact List
Ying Li
contact affiliationGuangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology
contact emailliying@gzhmu.edu.cn
lab head
Liwei Zhu
contact affiliationGuangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology
contact email337864188@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI