PXD056926-1

PXD056926 is an original dataset announced via ProteomeXchange.

Title	Fusing Engineered Bacterial Strains with NIR-II AIEgen for Multimodal Image-guided Phototherapy and Immunotherapy
Description	we present an aggregation-induced emission (AIE) - bacteria hybrid bionic robot to address the above issues. This bionic robot is composed of a multifunctional AIE molecule, INX-2 and Escherichia coli Nissle 1917 (EcN), i.e. EcN@INX-2. The robot is characterized by NIR-II fluorescence emission with efficient photodynamic and photothermal effects and tumor targeting, which was realized by INX-2 and EcN respectively, EcN@INX-2 achieved in vivo multimodal imaging and therapy of the tumors through multiple mechanisms including the activation of anti-tumor immunity, photodynamic and photothermal therapy in CT26 tumor-bearing female mice.
HostingRepository	iProX
AnnounceDate	2024-10-18
AnnouncementXML	Submission_2024-10-17_20:23:41.869.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Liwei Zhu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-17 20:23:29	ID requested
⏵ 1	2024-10-17 20:23:42	announced
2	2025-08-21 20:12:58	announced	2025-08-22: Add info.

Dataset with its publication pending

submitter keyword: Aggregation-induced emission, Bacteria, Bionic Robot, Phototheranostics, Immunotherapy

Ying Li
contact affiliation	Guangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology
contact email	liying@gzhmu.edu.cn
lab head
Liwei Zhu
contact affiliation	Guangzhou Medical University Innovation Research Center for AIE Pharmaceutical Biology
contact email	337864188@qq.com
dataset submitter

iProX dataset URI