PXD056776-2

PXD056776 is an original dataset announced via ProteomeXchange.

Title	Proteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via LC_MS
Description	Proteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via liquid chromatography–mass spectrometry (LC-MS), highlighting the expected LPS-induced increase in accumulation of proteases, ribonucleases (RNase) and other hydrolases.
HostingRepository	iProX
AnnounceDate	2024-10-14
AnnouncementXML	Submission_2025-08-21_20:09:21.915.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chengliang Lyu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-14 01:29:46	ID requested
1	2025-08-21 20:09:01	announced
⏵ 2	2025-08-21 20:09:23	announced	2025-08-22: Add info.

Lyu C, He Z, Hu X, Wang S, Qin M, Zhu L, Li Y, Yang F, Jiao Z, Zhang X, Lu G, Wang E, Hu Y, Zhai Y, Wang Y, Huang W, Wang D, Cui Y, Pang X, Liu X, Kamiya H, Ma G, Wei W, Lysosomal "TRAP": a neotype modality for clearance of viruses and variants. Nat Commun, 15(1):10155(2024) [pubmed]

submitter keyword: Hydrolase, Macrophage lysosome, LPS

Wei Wei
contact affiliation	Institute of Process Engineering, Chinese Academy of Sciences
contact email	weiwei@ipe.ac.cn
lab head
Chengliang Lyu
contact affiliation	Institute of Process Engineering, Chinese Academy of Sciences
contact email	sundays1994@163.com
dataset submitter

iProX dataset URI