PXD056692-1

PXD056692 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics analysis reveals a protein concentration effect of neat urine compared to urine EVs
Description	Research in urine proteomics and extracellular vesicles (EV) has gained increasing traction in biomarker research. Previous studies have suggested that both can be affected by urine protein concentration, however, there is a lack of data on the combined effect on urine proteomics. Here, we assessed the difference in proteomic signature in neat urine and urine enriched for EV at two protein concentrations, using two separate enrichment methods.
HostingRepository	PRIDE
AnnounceDate	2025-07-11
AnnouncementXML	Submission_2025-07-11_08:46:19.662.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Laura Dagley
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-10 05:58:12	ID requested
⏵ 1	2025-07-11 08:46:20	announced

10.1021/ACS.JPROTEOME.5C00060;

submitter keyword: urine extracellular vesicles, proteinuria, kidney biomarkers, urine proteomics

A/Prof. Andrew Webb
contact affiliation	The Walter and Eliza Hall Institute of Medical Research Associate Professor of Medical Biology, University of Melbourne, Australia
contact email	webb@wehi.edu.au
lab head
Laura Dagley
contact affiliation	WEHI
contact email	dagley.l@wehi.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/07/PXD056692

PRIDE project URI

• PRIDE
  1. PXD056692
     1. Label: PRIDE project
     2. Name: Quantitative proteomics analysis reveals a protein concentration effect of neat urine compared to urine EVs