PXD056590-2
PXD056590 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Lactate remodulates the OXPHOS of Tregs by inducing N-glycosylation in mitochondria via transcription and translocation of MGAT1 |
| Description | Proteomic data of control and lactate-treated Naive Treg and Memory Treg |
| HostingRepository | iProX |
| AnnounceDate | 2024-10-04 |
| AnnouncementXML | Submission_2025-09-03_00:19:20.990.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jian Gu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-10-08 00:59:18 | ID requested | |
| 1 | 2024-10-08 00:59:34 | announced | |
| ⏵ 2 | 2025-09-03 00:19:21 | announced | 2025-09-03: Add info. |
Publication List
| Zhou J, Gu J, Qian Q, Zhang Y, Huang T, Li X, Liu Z, Shao Q, Liang Y, Qiao L, Xu X, Chen Q, Xu Z, Li Y, Gao J, Pan Y, Wang Y, O'Connor R, Hippen KL, Lu L, Blazar BR, Lactate supports Treg function and immune balance via MGAT1 effects on N-glycosylation in the mitochondria. J Clin Invest, 134(20):(2024) [pubmed] |
Keyword List
| submitter keyword: Treg proteomic data |
Contact List
| Ling Lv | |
|---|---|
| contact affiliation | Affiliated Hospital of Xuzhou Medical University |
| contact email | lvling@njmu.edu.cn |
| lab head | |
| Jian Gu | |
| contact affiliation | The First Affiliated Hospital of Nanjing Medical University |
| contact email | gujian@njmu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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