PXD056553-1

PXD056553 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative proteomic and lipidomic analysis of LNCaP and C4-2 cell lines during CRPC progression
Description	Prostate cancer (PCa) is one of the most common cancers diagnosed in men in the world. The majority of patients develop resistant to androgen deprovation therapy, leading to castration-resistant PCa (CRPC). CRPC have a poorer prognosis and developing metastasis compared to hormone-sensitive PCa. To chracterize for new regulators of progression from HSPC to CRPC, LNCaP and C4-2 cells were selected as HSPC and CRPC, respectively. A comparative assessment of proein expression characteristics between two cells may provide insight into the regulatory landscape of CRPC.
HostingRepository	PRIDE
AnnounceDate	2025-11-10
AnnouncementXML	Submission_2025-11-09_16:39:49.469.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hyunchae Sim
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	iodoacetamide derivatized residue
Instrument	GCMS-QP2010SE; Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-07 09:32:48	ID requested
⏵ 1	2025-11-09 16:39:50	announced

Publication List

Sim H, Bae S, Park CW, Choi SY, Liu KH, Lee EH, Kim BS, Chung JW, Ha YS, Lee JN, Lee W, Kwon TG, Lee S, Lipid Metabolic Reprogramming During Progression to Castration-resistant Prostate Cancer Identified by Quantitative Proteomics. Cancer Genomics Proteomics, 22(6):940-952(2025) [pubmed]
10.21873/cgp.20548;

Sim H, Bae S, Park CW, Choi SY, Liu KH, Lee EH, Kim BS, Chung JW, Ha YS, Lee JN, Lee W, Kwon TG, Lee S, Lipid Metabolic Reprogramming During Progression to Castration-resistant Prostate Cancer Identified by Quantitative Proteomics. Cancer Genomics Proteomics, 22(6):940-952(2025) [pubmed]

10.21873/cgp.20548;

Keyword List

submitter keyword: Human, Prostate cancer, proteomics, lipidomics, GC-MS/MS, LC-MS/MS

submitter keyword: Human, Prostate cancer, proteomics, lipidomics, GC-MS/MS, LC-MS/MS

Contact List

Sangkyu Lee
contact affiliation	School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Korea
contact email	sangkyu@skku.edu
lab head
Hyunchae Sim
contact affiliation	Sungkyunkwan University
contact email	simhc0714@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD056553
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD056553

PRIDE project URI

Repository Record List

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