PXD056439-1

PXD056439 is an original dataset announced via ProteomeXchange.

Title	Mass spectrometry of histone post-translational modifications in WT and KMT2C/2D dKO urothelial cells
Description	KMT2C and KMT2D are two of the frequently mutated epigenetic modifiers in urothelial cancer. To compare the histone post-translational modification with Kmt2c/d loss, we performed mass spectrometry analysis of histones from Kmt2c/d WT and dKO urothelial cells.
HostingRepository	PRIDE
AnnounceDate	2025-01-08
AnnouncementXML	Submission_2025-01-08_12:05:22.295.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Naitao Wang
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monomethylated residue; acetylated residue
Instrument	TSQ Quantiva

Revision	Datetime	Status	ChangeLog Entry
0	2024-10-02 01:24:00	ID requested
⏵ 1	2025-01-08 12:05:22	announced

10.1038/S41588-024-02015-Y;

submitter keyword: Mouse urothelial cells, KMT2C, KMT2D, histone post-translational modification

Yu Chen
contact affiliation	Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, USA
contact email	cheny1@mskcc.org
lab head
Naitao Wang
contact affiliation	Memorial Sloan Kettering Cancer Center
contact email	wangnaitao@hotmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/01/PXD056439

PRIDE project URI

• PRIDE
  1. PXD056439
     1. Label: PRIDE project
     2. Name: Mass spectrometry of histone post-translational modifications in WT and KMT2C/2D dKO urothelial cells