PXD056373-1

PXD056373 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomic Analysis of Extracellular Vesicles Derived from Human Pluripotent Stem Cells
Description	Extracellular vesicles (EVs) and secretory factors are key to intercellular communication, yet their molecular dynamics in human pluripotent stem cells (hPSCs) are not well understood. We identified a key EV surface protein that regulates hPSC stemness, enhances growth, and promotes EV endocytosis. EV internalization helps reduce oxidative stress and cell death by transporting redox and stress response proteins, highlighting the importance of EV surface proteins in hPSC self-renewal and survival.
HostingRepository	PRIDE
AnnounceDate	2025-02-14
AnnouncementXML	Submission_2025-02-14_00:08:44.441.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Youngseok Lee
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-30 02:37:34	ID requested
⏵ 1	2025-02-14 00:08:44	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: extracellular vesicles,Human pluripotent stem cells

submitter keyword: extracellular vesicles,Human pluripotent stem cells

Contact List

Jong-Hoon Kim
contact affiliation	Korea University
contact email	jhkim@korea.ac.kr
lab head
Youngseok Lee
contact affiliation	Korea university
contact email	ddtys82077@naver.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD056373
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD056373

PRIDE project URI

Repository Record List

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