PXD056257-1

PXD056257 is an original dataset announced via ProteomeXchange.

Title	Novel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
Description	Novel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2
HostingRepository	PRIDE
AnnounceDate	2025-12-10
AnnouncementXML	Submission_2025-12-10_12:30:51.395.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ilah Bok
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-25 12:47:02	ID requested
⏵ 1	2025-12-10 12:30:51	announced

Dataset with its publication pending

submitter keyword: NRF2,KEAP1, CUL3

Michael B. Major
contact affiliation	Department of Cell Biology and Physiology, Washington University in St Louis, St Louis, Missouri, USA; Department of Otolaryngology/Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri, USA.
contact email	bmajor@wustl.edu
lab head
Ilah Bok
contact affiliation	Washington University School of Medicine in St. Louis
contact email	ilahbok@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD056257

PRIDE project URI

• PRIDE
  1. PXD056257
     1. Label: PRIDE project
     2. Name: Novel KEAP1 activator targeting C151 enhances CUL3 binding and decreases NRF2