PXD055809-1

PXD055809 is an original dataset announced via ProteomeXchange.

Title	ERK activation waves coordinate mechanical cell competition leading to collective onslaught of bacterially-infected cells
Description	In this study, we investigated how biochemical signaling, and in particular extracellular signal-regulated kinase (ERK) activity waves, coordinate the mechanical battle between Listeria monocytogenes infected and surrounder uninfected epithelial cells. We explored the collective infected cell extrusion using live-cell imaging, proteomics, atomic force microscopy (AFM), traction force microscopy (TFM) and additional approaches.
HostingRepository	PRIDE
AnnounceDate	2024-12-18
AnnouncementXML	Submission_2024-12-18_00:22:21.823.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ana Velic
SpeciesList	scientific name: Listeria monocytogenes; NCBI TaxID: 1639; scientific name: Canis familiaris (Dog) (Canis lupus familiaris); NCBI TaxID: 9615;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-12 01:40:38	ID requested
⏵ 1	2024-12-18 00:22:22	announced

10.2139/SSRN.4967745;

submitter keyword: host-pathogen interactions,Cell competition, collective cell extrusion, Listeria monocytogenes, Shigella flexneri, zebrafish models, bacterial infection, ERK activation waves, cell biomechanics, epithelial cells

Effie Bastounis
contact affiliation	Bastounis lab, IMIT, CMFI, University of Tübingen, Germany
contact email	Effie.Bastounis@uni-tuebingen.de
lab head
Ana Velic
contact affiliation	University of Tuebingen
contact email	a.velic@uni-tuebingen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/12/PXD055809

PRIDE project URI

• PRIDE
  1. PXD055809
     1. Label: PRIDE project
     2. Name: ERK activation waves coordinate mechanical cell competition leading to collective onslaught of bacterially-infected cells