PXD055590-1

PXD055590 is an original dataset announced via ProteomeXchange.

Title	Multi-organ quantitative proteome map following ASNase treatment
Description	We applied the ultra-fast proteome profiling workflow to tissues collected from NSG mice treated with PBS (vehicle control), 20,000 U/kg ASNaseWT (Spectrila®), or 20,000 U/kg ASNaseQ59L for 0, 1, 3, 5, and 8 d. At each time point, mice were euthanized, and 13 tissues were collected, including subcutaneous white adipose tissue (SQWAT), gonadal adipose tissue (GAT), lung, spleen, stomach, small and large intestine, liver, kidney, heart, leg muscle, brain, and bone marrow. A total of 507 collected tissue samples were processed for quantitative proteome profiling.
HostingRepository	PRIDE
AnnounceDate	2026-01-14
AnnouncementXML	Submission_2026-01-14_06:19:33.488.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yun Xiong
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2024-09-05 08:12:14	ID requested
⏵ 1	2026-01-14 06:19:34	announced

Dataset with its publication pending

submitter keyword: Asparaginase, Drug, Proteomics,Mass spectrometry, Multi-organ

Philip L. Lorenzi
contact affiliation	1) Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77030, USA 2) Proteomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77030, USA 3) Metabolomics Core Facility, Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center (MDACC), Houston, TX 77030, USA
contact email	PLLorenzi@mdanderson.org
lab head
Yun Xiong
contact affiliation	UT. MD. Anderson Cancer Center
contact email	yxiong3@mdanderson.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD055590

PRIDE project URI

• PRIDE
  1. PXD055590
     1. Label: PRIDE project
     2. Name: Multi-organ quantitative proteome map following ASNase treatment