PXD055444-1
PXD055444 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of the effects of Shenzhu Tiaopi granules on model rats with type 2 diabetes mellitus |
Description | In total, 5856 proteins were identified via proteomics analysis, 97 of which were significantly differentially expressed in the liver and affected fatty acid metabolism, unsaturated fatty acid biosynthesis, the peroxisome proliferator-activated receptor (PPAR) signalling pathway, pyruvate metabolism, and terpenoid backbone biosynthesis. Screening identified 10 target proteins, including perilipinā2 (Plin2), Pdk4, farnesyl diphosphate synthase (Fdps) and Fdft1. Among these, the key proteins were Plin2 and Fdps, which were found to be associated with the PPAR signalling pathway and terpenoid backbone biosynthesis via the relationship networks |
HostingRepository | iProX |
AnnounceDate | 2024-08-30 |
AnnouncementXML | Submission_2024-09-01_20:14:25.335.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jindong Zhao |
SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
ModificationList | No PTMs are included in the dataset |
Instrument | timsTOF Pro |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-09-01 20:14:13 | ID requested | |
⏵ 1 | 2024-09-01 20:14:25 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: type 2 diabetes mellitus, improving hyperglycaemia, proteomics, Fdps, Plin2, Shenzhu Tiaopi granule |
Contact List
Jindong Zhao | |
---|---|
contact affiliation | the First Affiliated Hospital of Anhui University of Chinese Medicine |
contact email | fangzhaohui1111@163.com |
lab head | |
Jindong Zhao | |
contact affiliation | the First Affiliated Hospital of Anhui University of Chinese Medicine |
contact email | zhaojindong1111@outlook.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |