PXD055129 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic profiling of UV damage repair patches |
| Description | DNA damage compromises not only genome stability but also the integrity of the chromatin template, which plays a central role in controlling cell identity. Our understanding of chromatin repair mechanisms is very incomplete. To bridge this knowledge gap, here we devised a novel proteomic strategy to characterize dynamic changes in the chromatin landscape during the repair of UV-induced DNA lesions in human cells, in a quantitative, unbiased and time-resolved manner. Based on the established IPOND methodology (Isolation of Proteins On Nascent DNA), we called this method IPOND-R for Isolation of Proteins On Nascent DNA at Repair sites. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-12_06:16:31.436.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD055129 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Yohann Couté |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Q Exactive HF; Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-08-23 05:49:26 | ID requested | |
| ⏵ 1 | 2026-01-12 06:16:31 | announced | |
Publication List
Keyword List
| submitter keyword: UV damage repair,Chromatin, IPOND, nanoLC-MS/MS |
Contact List
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| lab head | |
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD055129
- Label: PRIDE project
- Name: Proteomic profiling of UV damage repair patches
