PXD054912-1

PXD054912 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Dataset14_SUDHL4 SAMHD1 KO 1h 8h Gemcitabine IMPRINTS
Description	SUDHL4 SAMHD1 knockout cells were treated with 24uM gemcitabine for 1h and 8h (with 8h vehicle control), collected and subjected to CETSA heating, followed by cell lysis, isolation of soluble fraction and sample preparation for MS including digestion, desalting, TMT labeling, offline fractionation and pooling.
HostingRepository	jPOST
AnnounceDate	2025-06-12
AnnouncementXML	Submission_2025-06-11_20:36:31.858.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ying Yu Liang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; TMT6plex reporter+balance reagent N-acylated residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-15 00:51:03	ID requested
⏵ 1	2025-06-11 20:36:32	announced

Publication List

Liang YY, Khalid K, Le HV, Teo HMV, Raitelaitis M, Gerault MA, Lee JJH, Lyu J, Chan A, Jeyasekharan AD, Tam WL, Nordlund P, Prabhu N, MS CETSA deep functional proteomics uncovers DNA repair programs leading to gemcitabine resistance. Nat Commun, 16(1):4234(2025) [pubmed]

Liang YY, Khalid K, Le HV, Teo HMV, Raitelaitis M, Gerault MA, Lee JJH, Lyu J, Chan A, Jeyasekharan AD, Tam WL, Nordlund P, Prabhu N, MS CETSA deep functional proteomics uncovers DNA repair programs leading to gemcitabine resistance. Nat Commun, 16(1):4234(2025) [pubmed]

Keyword List

submitter keyword: TMT10, MS-CETSA, IMPRINTS, Gemcitabine

submitter keyword: TMT10, MS-CETSA, IMPRINTS, Gemcitabine

Contact List

Liang Ying Yu
lab head
Ying Yu Liang
contact affiliation	ASTAR
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003288/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003288/