PXD054773 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Data-independent acquisition proteomics enhances cellular nucleic acid binding protein characterization in colitis data1 |
| Description | We developed a robust workflow for in-depth analysis of NABPs, which combining immobilized metal affinity chromatography capture and data-independent acquisition. This workflow enhances the identification and quantification of NABPs. We then applied this workflow to colitis mouse and discovered epigenetic processes, particularly histone methylation was significantly changed in spleen. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-01 |
| AnnouncementXML | Submission_2025-11-30_16:09:44.845.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Huiyu Wang |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-08-10 02:52:20 | ID requested | |
| ⏵ 1 | 2025-11-30 16:09:45 | announced | |
Publication List
| 10.1093/nar/gkaf1167; |
| Wang H, Zhu J, Li S, Zhang L, Guo M, Zhao J, Zhang Y, Cao C, Hu S, Xiao H, Massive deciphering of the tissue nucleic acid-binding proteome via affinity chromatography integrated with data-independent acquisition-based proteomics. Nucleic Acids Res, 53(21):(2025) [pubmed] |
Keyword List
| submitter keyword: nucleic acid binding protemoics, LC/MS-MS,Colitis |
Contact List
| Hua Xiao |
|---|
| contact affiliation | State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, China. |
| contact email | huaxiao@sjtu.edu.cn |
| lab head | |
| Huiyu Wang |
|---|
| contact affiliation | 18272583259 |
| contact email | lizlemon@sjtu.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD054773 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD054773
- Label: PRIDE project
- Name: Data-independent acquisition proteomics enhances cellular nucleic acid binding protein characterization in colitis data1
