PXD054671-2

PXD054671 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Confirmation of SOMAmer® Specificity in Serum using Mass Spectrometry
Description	Experiments were conducted to confirm SOMAmer® reagent specificity by enrichment in serum from elderly subjects (>65 years, male n=1 and female n=1, purchased from commercial vendor) followed by measurement using data dependent analysis (DDA). Non-specific binding was assessed in the biological matrix by comparing target protein spectral counts in the respective enrichment to pull down using a reagent generated against the bacterial protein CysH. A positive hit was defined as target protein detection with a minimum of 2 spectral counts and signal over CysH background greater than 10X (if applicable).
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_06:55:54.866.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD054671
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Nancy Finkel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-07 05:03:04	ID requested
1	2024-08-22 08:45:00	announced
⏵ 2	2024-10-22 06:55:55	announced	2024-10-22: Updated project metadata.

Publication List

10.6019/PXD054671;
10.1038/S43587-024-00693-1;

10.6019/PXD054671;

10.1038/S43587-024-00693-1;

Keyword List

submitter keyword: LC-MSMS,Human Serum, Aptamer

submitter keyword: LC-MSMS,Human Serum, Aptamer

Contact List

Lori Jennings
contact affiliation	Novartis
contact email	lori.jennings@novartis.com
lab head
Nancy Finkel
contact affiliation	Novartis
contact email	nancy.finkel@novartis.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD054671
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD054671

PRIDE project URI

Repository Record List

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