PXD054668 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The glomerular circadian clock temporally regulates basement membrane dynamics and podocyte glucocorticoid response |
| Description | Kidneys were collected from wildtype mice over the course of two circadian cycles (every 4 hours for 48 hours), snap frozen, and later prepared for circadian proteomic analysis The purpose of this study was to investigate the correlation between rhythmic matrix gene expression and matrix protein abundance. To focus our analysis on the kidney matrix, we generated a matrix-enriched fraction. Samples were prepared for label-free mass spectrometry-based proteomics to define rhythmic changes in the protein composition of mouse kidneys. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-02-02 |
| AnnouncementXML | Submission_2026-02-02_07:37:19.499.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD054668 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Mychel Morais |
| SpeciesList | scientific name: Danio rerio (Zebrafish) (Brachydanio rerio); NCBI TaxID: NEWT:7955; scientific name: Nicotiana tabacum (Common tobacco); NCBI TaxID: NEWT:4097; scientific name: Heliocidaris erythrogramma (Sea urchin); NCBI TaxID: NEWT:7634; scientific name: Hordeum vulgare (Barley); NCBI TaxID: NEWT:4513; scientific name: Ictalurus punctatus (Channel catfish); NCBI TaxID: NEWT:7998; scientific name: Enterococcus faecalis (Streptococcus faecalis); NCBI TaxID: NEWT:1351; scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; scientific name: Halobacterium salinarum; NCBI TaxID: NEWT:2242; scientific name: Cercopithecus aethiops (Green monkey) (Grivet); NCBI TaxID: NEWT:9534; scientific name: Bos taurus (Bovine); NCBI TaxID: NEWT:9913; scientific name: Merluccius bilinearis (Silver hake); NCBI TaxID: NEWT:79698; scientific name: Hepatitis C virus subtype 1a; NCBI TaxID: NEWT:31646; scientific name: Helicobacter pylori J99 (Campylobacter pylori J99); NCBI TaxID: NEWT:85963; scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: NEWT:7227; scientific name: Gadus morhua (Atlantic cod); NCBI TaxID: NEWT:8049; scientific name: Bombyx mori (Silk moth); NCBI TaxID: NEWT:7091; scientific name: Equus caballus (Horse); NCBI TaxID: NEWT:9796; scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; scientific name: Gallus gallus (Chicken); NCBI TaxID: NEWT:9031; scientific name: Candida albicans (Yeast); NCBI TaxID: NEWT:5476; scientific name: Brassica napus (Rape); NCBI TaxID: NEWT:3708; scientific name: Caenorhabditis elegans; NCBI TaxID: NEWT:6239; scientific name: Mesocricetus auratus (Golden hamster); NCBI TaxID: NEWT:10036; scientific name: Dictyostelium discoideum (Slime mold); NCBI TaxID: NEWT:44689; scientific name: Escherichia coli; NCBI TaxID: NEWT:562; scientific name: Macaca mulatta (Rhesus macaque); NCBI TaxID: NEWT:9544; scientific name: Cicer arietinum (Chickpea) (Garbanzo); NCBI TaxID: NEWT:3827; scientific name: Brassica oleracea var. botrytis (Cauliflower); NCBI TaxID: NEWT:3715; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-08-07 03:15:55 | ID requested | |
| ⏵ 1 | 2026-02-02 07:37:20 | announced | |
| 2 | 2026-02-04 09:09:25 | announced | 2026-02-04: Updated project metadata. |
Publication List
Keyword List
| submitter keyword: kidney matrix, podocytes, glomerular basement membrane,Circadian rhythm, glucocorticoids |
Contact List
| Rachel Lennon |
|---|
| contact affiliation | Division of Cell Matrix Biology and Regenerative Medicine, School of Biological Sciences, Faculty of Biology, Medical and Health Sciences. University of Manchester, UK. |
| contact email | rachel.lennon@manchester.ac.uk |
| lab head | |
| Mychel Morais |
|---|
| contact affiliation | The University of Manchester |
| contact email | mychel.morais@manchester.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD054668 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD054668
- Label: PRIDE project
- Name: The glomerular circadian clock temporally regulates basement membrane dynamics and podocyte glucocorticoid response
