PXD054576-1

PXD054576 is an original dataset announced via ProteomeXchange.

Title	Induction and maintenance of mouse totipotent stem cells by a G-quadruplex unwinder
Description	Using small molecules to induce the establishment of totipotent stem cells is an important and challenging work. Here, we treated mouse embryonic stem cells (ESCs) with a G-quadruplex unwinder to transform them into totipotent cells, called G4TotiSC. We identified the whole cell protein expression levels of G4TotiSC and ESC by proteomic analysis. There were 4 samples in total, and ESC and G4TotiSC had two samples each. We identified a total of 10327 proteins, and 9093 comparable proteins.
HostingRepository	iProX
AnnounceDate	2024-08-05
AnnouncementXML	Submission_2024-08-05_01:06:51.268.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yuncong Wu
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-05 01:01:37	ID requested
⏵ 1	2024-08-05 01:06:51	announced

Dataset with its publication pending

submitter keyword: totipotent stem cells

chemical induction

maintenance

G-quadruplex

unwinding

Jinghong Li
contact affiliation	Tsinghua University
contact email	jhli@mail.tsinghua.edu.cn
lab head
Yuncong Wu
contact affiliation	Tsinghua University
contact email	675155730@qq.com
dataset submitter

iProX dataset URI