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PXD054569-1

PXD054569 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Analysis of blood protein markers for early detection and diagnosis of advanced adenomatous and colorectal cancer
Description	This study constructed a CRC early screening model using blood proteomics, achieving high accuracy and sensitivity in detecting early CRC and AA. We explored colorectal cancer (CRC)-related protein biomarkers by proteome-wide differential expression analysis based on a case-control design. The blood samples form 150 colorectal cancer (CRC) cases and 50 controls were collected. The blood samples from 50 individuals with advanced adenoma were also collected and analyzed in another subproject study. Plasma protein measurements were generated using the iodo Tandem Mass Tags (TMT)-6plex quantitative proteomics. Plasma proteomics data from all samples (150 CRC cases, 50 individuals with advanced adenoma, and 50 controls) were submitted.
HostingRepository	iProX
AnnounceDate	2024-08-03
AnnouncementXML	Submission_2024-08-05_00:27:20.188.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jingsun Wei
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-08-05 00:26:48	ID requested
⏵ 1	2024-08-05 00:27:20	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: early detection, colorectal cancer

Contact List

Qian Xiao
contact affiliation	The Second Affiliated Hospital, Zhejiang University School of Medicine
contact email	qxiao3@zju.edu.cn
lab head
Jingsun Wei
contact affiliation	The Second Affiliated Hospital, Zhejiang University School of Medicine
contact email	jingsunwei@zju.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI