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PXD054317-2

PXD054317 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of senescent translatome
DescriptionTo examine senescent translatome, we combined L-azidohomoalanine (AHA)-mediated labeling of newly synthesized proteins followed by click chemistry for biotin conjugation with the DiDBiT in proliferating and senescent cells. Senescence was induced using a stress-induced senescence model (bleomycin-induced senescence). We further examined the effect of EIF4H-S knockdown on the translatome using a shRNA targeting EIF4H-S.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_07:00:43.344.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD054317
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterJong-Seo Kim
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-07-28 22:44:05ID requested
12024-10-03 21:50:09announced
22024-10-22 07:00:43announced2024-10-22: Updated project metadata.
Publication List
10.6019/PXD054317;
Keyword List
ProteomeXchange project tag: Human Proteome Project
submitter keyword: Senescence, Translation
Contact List
Jong-Seo Kim
contact affiliationAssistant professor, School of Biological Sciences, Seoul National University
contact emailjongseokim@snu.ac.kr
lab head
Jong-Seo Kim
contact affiliationSchool of Biological Sciences, Seoul National University
contact emailjongseokim@snu.ac.kr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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