PXD053553-1
PXD053553 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Exploring changes in ARGs during chromium reduction by Bacillus cereus SH-1 exposed to chromium-contaminated wastewater: a functional analysis from gene to protease |
Description | This study researched the combined effects of hexavalent chromium (Cr(VI)) concentration and antibiotics on the ARGs of Bacillus cereus SH-1. As the Cr(VI) concentration increased, it triggered Reactive Oxygen Species (ROS) oxidative stress in SH-1, increased antioxidant enzyme activity, enhanced plasmid conjugative transfer and reduced the removal efficiency of Cr(VI) by SH-1. Meanwhile, antibiotic resistance varied with TET (Tetracycline) and AMC (Amoxicillin) MICs (minimum inhibitory concentration) rising and AZM (Azithromycin) and CL (Chloramphenicol) MICs decreasing with Cr(VI) induction. Overexpression of eight genes of the HAE-1 family efflux pumps was detected through metagenomics and proteomics. Co-contamination of Cr(VI) and antibiotics led to the emergence and spread of antibiotics resistant bacteria (ARBs). |
HostingRepository | iProX |
AnnounceDate | 2024-07-01 |
AnnouncementXML | Submission_2024-07-01_21:47:28.990.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Hui Wu |
SpeciesList | scientific name: Bacillus cereus C1L; NCBI TaxID: 1003239; |
ModificationList | No PTMs are included in the dataset |
Instrument | MassHunter Easy Access |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2024-07-01 21:46:10 | ID requested | |
⏵ 1 | 2024-07-01 21:47:29 | announced |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Bacillus cereus SH-1, Chromium Pollution Removal, Antibiotic Resistance, protease |
Contact List
Dongyun Du | |
---|---|
contact affiliation | South-Central Minzu University |
contact email | 1244584578@qq.com |
lab head | |
Hui Wu | |
contact affiliation | South-Central Minzu University |
contact email | 1280627787@qq.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |