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PXD053451-1

PXD053451 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSite-specific N-glycosylation Characterization of Monoclonal Immunoglobulins in Multiple Myeloma
DescriptionMonoclonal immunoglobulins (M-proteins) produced by clonal plasma cells are the main cause of multiple myeloma (MM), and hypocomplementemia is observed in some patients with MM. Previous studies have suggested that the glycosylation of immunoglobulins is associated with complement-mediated effector activities. However, the site-specific N-glycosylation of monoclonal immunoglobulins in MM and their effects on complement system activation remain unclear.
HostingRepositoryiProX
AnnounceDate2024-06-27
AnnouncementXMLSubmission_2024-06-27_00:25:37.778.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYong Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListdeaminated residue
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-27 00:24:37ID requested
12024-06-27 00:25:38announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: N-glycosylation, mass spectrometry, monoclonal immunoglobulins, multiple myeloma 
Contact List
Yong Zhang
contact affiliationWest China Hospital, Sichuan University
contact emailnankai1989@foxmail.com
lab head
Yong Zhang
contact affiliationWest China Hospital, Sichuan University
contact emailnankai1989@foxmail.com
dataset submitter
Full Dataset Link List
iProX dataset URI