PXD053363-1

PXD053363 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Afucosylated broadly neutralizing antibodies enhance clearance of HIV-1 infected cells through NK cell mediated killing
Description	A series of monoclonal antibodies (mAbs) against human immune deficiency virus (HIV) were prepared utilizing different variable regions targeting HIV epitopes in combination with glycoengineering to produce mAbs with low Fc fucosylation. This dataset pertains to the Fc N-glycosylation analysis of these mAbs.
HostingRepository	PRIDE
AnnounceDate	2024-07-30
AnnouncementXML	Submission_2024-07-30_09:21:30.541.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	David Falck
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	complex glycosylation; iodoacetamide derivatized residue
Instrument	impact HD

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-24 09:50:06	ID requested
⏵ 1	2024-07-30 09:21:30	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: LC-MS, monoclonal antibodies, HEK-293F cells, antibody glycosylation

submitter keyword: LC-MS, monoclonal antibodies, HEK-293F cells, antibody glycosylation

Contact List

David Falck
contact affiliation	Center for Proteomics and Metabolomics, Leiden University Medical Center, The Netherlands
contact email	d.falck@lumc.nl
lab head
David Falck
contact affiliation	Leiden University Medical Center
contact email	d.falck@lumc.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD053363
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD053363

PRIDE project URI

Repository Record List

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