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PXD053336-1

PXD053336 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
DescriptionThrough chemical probe screening, we uncovered a novel mechanism of RNA splicing in paclitaxel-resistant TNBC and identified PRMTs as therapeutic targets.
HostingRepositoryiProX
AnnounceDate2024-06-22
AnnouncementXMLSubmission_2024-06-24_00:07:12.964.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSheyu Zhang
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-24 00:06:12ID requested
12024-06-24 00:07:13announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: TNBC, paclitaxel-resistant , PRMT5, RNA-splicing, AURKB, mitosis
Contact List
Qin Wu
contact affiliationHangzhou Instititute of Medicine
contact emailwuqin@ibmc.ac.cn
lab head
Sheyu Zhang
contact affiliationHangzhou Instititute of Medicine
contact email2020213009@tju.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI