PXD053225-1

PXD053225 is an original dataset announced via ProteomeXchange.

Title	Label-Free Quantification Method for Assessing Sex from Modern and Ancient Bovine Tooth Enamel. PART III
Description	Identification of the sex of modern, fossil and archaeological animal remains offers many insights into their demography, mortality profiles and domestication pathways. However, due to manifold factors, sex determination of such remains is often impossible. To overcome this, we have developed an innovative protocol to determine an animal sex applying label-free quantification (LFQ) of two unique AmelY peptides ‘LRYPYP’ (AmelY;[M+2]2+ 404.7212 m/z) and ‘LRYPYPSY’ (AmelY;[M+2]2+ 529.7689 m/z) that are solely present in tooth enamel of males. we applied this method to eight (8) modern cattle (Bos taurus) and (12) twelve archaeological samples of Bos from a Neolithic sites of Beisamoun, Israel (8th–7th millennium BC). Our methodology correctly identified the sex of the modern samples and enabled determination of sex in the archaeological samples.
HostingRepository	PRIDE
AnnounceDate	2024-10-17
AnnouncementXML	Submission_2024-10-17_02:37:30.169.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Paula Kotli
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	monohydroxylated residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-18 23:00:40	ID requested
⏵ 1	2024-10-17 02:37:31	announced

10.1038/s41598-024-68603-4;

Kotli P, Morgenstern D, Bocquentin F, Khalaily H, Horwitz LK, Boaretto E, A label-free quantification method for assessing sex from modern and ancient bovine tooth enamel. Sci Rep, 14(1):18195(2024) [pubmed]

submitter keyword: Amels, LFQ, sex determination

Prof. Elisabetta Boaretto
contact affiliation	Weizmann Institute of Science Archeological Science
contact email	elisabetta.boaretto@weizmann.ac.il
lab head
Paula Kotli
contact affiliation	Weizmann Institute of Science
contact email	Paula.kotli@weizmann.ac.il
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/10/PXD053225

PRIDE project URI

• PRIDE
  1. PXD053225
     1. Label: PRIDE project
     2. Name: Label-Free Quantification Method for Assessing Sex from Modern and Ancient Bovine Tooth Enamel. PART III