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PXD053198-1

PXD053198 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleTrinucleotide cap analogs with tetraphosphate modifications: interaction partners in HEK293F cell lysate
DescriptionThis dataset was acquired to identify human proteins binding to tetraphosphate mRNA cap analogs. Affinity resins were derivatized with tetraphosphate mRNA cap analogs or a trinucleotide cap control and affinity purification performed in HEK293F cell extracts. The pulled-down proteins were eluted using soluble cap analogs, subjected to digestion with trypsin, TMT labelling, and nLC-MS/MS analysis.
HostingRepositoryPRIDE
AnnounceDate2024-10-02
AnnouncementXMLSubmission_2024-10-02_04:14:15.053.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterRemigiusz Serwa
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-06-18 05:20:35ID requested
12024-10-02 04:14:15announced
22024-10-22 07:00:24announced2024-10-22: Updated project metadata.
Publication List
10.1093/NAR/GKAE763;
Keyword List
submitter keyword: tetraphosphate, affinity purification, HEK293F, 5′ cap,mRNA
Contact List
Jacek Jemielity
contact affiliationCentre of New Technologies, University of Warsaw, Banacha 2C, 02-097 Warsaw, Poland
contact emailj.jemielity@cent.uw.edu.pl
lab head
Remigiusz Serwa
contact affiliationThe International Institute of Molecular Mechanisms and Machines, Polish Academy of Sciences
contact emailr.serwa@imol.edu.pl
dataset submitter
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Dataset FTP location
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