PXD053186-2

PXD053186 is an original dataset announced via ProteomeXchange.

Title	Comprehensive Proteomic Characterization of Scar Formation in Urethral Stricture Disease
Description	Male urethral stricture disease (USD) is characterized by scar formation, whose molecular mechanism is still lack. In this study, we performed comprehensive proteomic landscape of USD with 12 scar tissues and 5 matched normal adjacent tissues (NATs). Comparative analysis disclosed the ECM signaling and complement cascade were overrepresented in the scar tissues, in which COL11A1, CNN2, and CD248 would play positive impacts.
HostingRepository	iProX
AnnounceDate	2024-06-18
AnnouncementXML	Submission_2024-12-12_19:05:45.138.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lingling Li
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-17 19:49:25	ID requested
1	2024-06-18 01:22:52	announced
⏵ 2	2024-12-12 19:05:48	announced	2024-12-13: Update information.

Gao J, Liu H, Li L, Guo C, Wang Z, Cheng M, Tan S, Chen L, Shi J, Wu H, Feng C, Yu G, Ding C, Comprehensive proteomic characterization of urethral stricture disease in the Chinese population. Front Mol Biosci, 11():1401970(2024) [pubmed]

submitter keyword: Proteomics, USD, scar formation, immune infiltration, therapeutic targets

Chen Ding
contact affiliation	Fudan university
contact email	chend@fudan.edu.cn
lab head
Lingling Li
contact affiliation	Fudan university
contact email	lill18@fudan.edu.cn
dataset submitter

iProX dataset URI