PXD053080-1

PXD053080 is an original dataset announced via ProteomeXchange.

Title	USP20 promotes T-ALL evolution by deubiquitinating modified HIF1A
Description	Qualitative analysis of proteome is to study the types and quantities of proteome identified by samples under different conditions, and to perform functional analysis of the identified proteins, so as to provide reference information for quantitative and modification analysis of high-throughput proteins.In order to explore how USP20 plays a role in T-ALL through deubiquitination, we investigated the substrate protein of USP0 by protein determination spectrometry.
HostingRepository	PRIDE
AnnounceDate	2025-10-13
AnnouncementXML	Submission_2025-10-12_16:07:38.578.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zimu Zhang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-13 07:34:32	ID requested
⏵ 1	2025-10-12 16:07:39	announced

10.1016/j.apsb.2025.07.003;

Xu L, Zhang Z, Yu J, Ji T, Cheng J, Fei X, Chu X, Tao Y, Xu Y, Yang P, Liu W, Li G, Zhang Y, Li Y, Zhang F, Yang Y, Zhou B, Wu Y, Wei Z, Chen Y, Wang J, Wu D, Li X, Yang Y, Qian G, Yin H, Wu S, Zhang S, Liu D, Fan JJ, Shi L, Wang X, Hu S, Lu J, Pan J, HIF1A deubiquitination. Acta Pharm Sin B, 15(9):4751-4771(2025) [pubmed]

submitter keyword: USP20,HIF1A

Ling Xu
contact affiliation	Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
contact email	zimmer89@sina.com
lab head
Zimu Zhang
contact affiliation	Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
contact email	zimmer89@sina.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD053080

PRIDE project URI

• PRIDE
  1. PXD053080
     1. Label: PRIDE project
     2. Name: USP20 promotes T-ALL evolution by deubiquitinating modified HIF1A