PXD053000-1
PXD053000 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | isoDTB-ABPP Cysteine Chemoproteomic Profiling for bigelovin |
| Description | isoDTB-ABPP Cysteine Chemoproteomic Profiling was used to detect the targets of bigelovin in NLRP3 inflammasome activation. LPS and ATP induced bone marrow derived macrophages were adopted for the experiment in three biological replicates. Cell was treated with DMSO and bigelovin respectively. The cell lysate was incubated with IA-alkyne, followed by click reaction. The DMSO group was labeled by light isoDTB tags and the bigelovin group was labeled by heavy isoDTB tags. |
| HostingRepository | iProX |
| AnnounceDate | 2024-06-11 |
| AnnouncementXML | Submission_2024-06-11_00:11:45.926.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chengli Yu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-06-11 00:10:56 | ID requested | |
| ⏵ 1 | 2024-06-11 00:11:46 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: isoDTB-ABPP, bigelovin |
Contact List
| Chengli Yu | |
|---|---|
| contact affiliation | Jiangsu Key Laboratory for Functional Substances of Chinese Medicine |
| contact email | yuchengli@njucm.edu.cn |
| lab head | |
| Chengli Yu | |
| contact affiliation | Nanjing University of Chinese Medicine |
| contact email | yuchengli@njucm.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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