PXD052861 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Plasma Proteomics Analysis of the Cooperative Health Research in South Tyrol (CHRIS) Study, Study Pools |
Description | The Cooperative Health Research in South Tyrol (CHRIS) study is a single-site population-based study aimed to investigate the genetic and molecular basis of common age-related chronic conditions and their interaction with lifestyle and environment. In recent work, we have been evaluating the impact of age, sex and diet, amongst others, on the human metabolome. Moreover, gene-metabolite associations, as well as genetic and metabolomic determinants of disease, have been investigated. Using Scanning SWATH acquisition on Triple TOF 6600 instruments (Sciex) we created a MS-based plasma proteomics data set with low technical variability for n = 3,632 CHRIS participants. We performed a general exploratory analysis of the data set to identify relevant factors affecting the plasma proteome, including commonly used drugs. We found hormonal contraceptives to be the main factor explaining the variation in this data set. Here we present the pooled study samples. |
HostingRepository | PRIDE |
AnnounceDate | 2024-07-08 |
AnnouncementXML | Submission_2024-07-08_04:30:11.612.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Clemens Dierks |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | TripleTOF 6600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-06-05 06:29:13 | ID requested | |
⏵ 1 | 2024-07-08 04:30:12 | announced | |
Publication List
Keyword List
submitter keyword: Plasma, Human |
Contact List
Markuer Ralser |
contact affiliation | Department of Biochemistry, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany Berlin Institute of Health (BIH) at Charité Universitätsmedizin Berlin, Berlin, Germany The Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Roosevelt Dr, Headington, Oxford OX3 7BN, UK |
contact email | markus.ralser@charite.de |
lab head | |
Clemens Dierks |
contact affiliation | Institute of Biochemistry, Charité Universitaetsmedizin Berlin, Germany |
contact email | clemens.dierks@charite.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD052861 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052861
- Label: PRIDE project
- Name: Plasma Proteomics Analysis of the Cooperative Health Research in South Tyrol (CHRIS) Study, Study Pools