PXD052852-1

PXD052852 is an original dataset announced via ProteomeXchange.

Title	MS-based label-free quantification of the ratio of AIFM1/AK2 peptide intensities from CTRL or IA-treated FLAG pull-downs
Description	This project aims to utilize mass spectrometry (MS) for label-free quantification of the peptide intensity ratio of AIFM1 (Apoptosis-Inducing Factor Mitochondrion-Associated 1) and AK2 (Adenylate Kinase 2) in control (CTRL) and iodoacetamide (IA)-treated FLAG pull-down samples. The approach focuses on analyzing the variations in peptide intensities to understand the differential protein interactions and modifications resulting from IA treatment.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_01:53:18.628.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Fabian Schildhauer
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-05 03:02:18	ID requested
⏵ 1	2025-05-06 01:53:19	announced

Dataset with its publication pending

submitter keyword: DIA,AP-MS

Juri Rappsilber
contact affiliation	Technische Universität Berlin, Chair of Bioanalytics, 10623 Berlin, Germany
contact email	juri.rappsilber@tu-berlin.de
lab head
Fabian Schildhauer
contact affiliation	Technische Universität Berlin
contact email	schildhauer@tu-berlin.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD052852

PRIDE project URI

• PRIDE
  1. PXD052852
     1. Label: PRIDE project
     2. Name: MS-based label-free quantification of the ratio of AIFM1/AK2 peptide intensities from CTRL or IA-treated FLAG pull-downs