PXD052843-1

PXD052843 is an original dataset announced via ProteomeXchange.

Title	Limb remote ischemic preconditioning promotes angiogenesis in ischemic stroke rats by targeting HIF-1a/VEGF
Description	The initial factor in the occurrence, development, and prognosis of cerebral ischemia is vascular dysfunction in the brain, and vascular remodeling of the brain is the key therapeutic target and strategy for ischemic tissue repair. Limb remote ischemic preconditioning exhibits potential pleiotropic protective effects in many brain-related diseases, including stroke.Whether limb remote ischemic preconditioning has other effects such as vascular protective effects and the detailed mechanism by which limb remote ischemic preconditioning improves pathology and angiogenesis in cerebral ischemia remains to be further elucidated. The present study was designed to investigate whether limb remote ischemic preconditioning protects vascular structure and promotes angiogenesis in cerebral ischemic rats.
HostingRepository	iProX
AnnounceDate	2024-06-05
AnnouncementXML	Submission_2024-06-04_20:23:30.642.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tianxiu Zheng
SpeciesList	scientific name: Rattus rattus; NCBI TaxID: 10117;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-04 20:13:54	ID requested
⏵ 1	2024-06-04 20:23:31	announced

Dataset with its publication pending

submitter keyword: Limb remote ischemic preconditioning, MCAO, HIF-1a, exosome

Dingtai Wei
contact affiliation	Ningde Municipal Hospital Affiliated to Ningde Normal University
contact email	wdtai83@163.com
lab head
Tianxiu Zheng
contact affiliation	Ningde Municipal Hospital Affiliated to Ningde Normal University
contact email	1064551272@qq.com
dataset submitter

iProX dataset URI