PXD052816-1

PXD052816 is an original dataset announced via ProteomeXchange.

Title	Full transcriptome and proteome analysis of the mechanism of tuberculosis Ag85B-Fc2a in alleviating allergic asthma in mice
Description	In the early stage, an OVA-induced mouse allergic asthma model was constructed and treated with Ag85B-Fc2a fusion protein, which proved that Ag85B-Fc2a fusion protein could reduce the infiltration of inflammatory cells in the lungs and had a therapeutic effect on asthma。In order to further explore the mechanism of action, we carried out transcriptomics and proteomic sequencing, screened out related genes and proteins, enriched them, and focused on pathways with significant differences. In the later stage, q-PCR and Western-blot experiments will be performed for verification.
HostingRepository	iProX
AnnounceDate	2024-06-04
AnnouncementXML	Submission_2024-06-03_23:50:56.356.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Tiansong Wang
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-06-03 23:50:19	ID requested
⏵ 1	2024-06-03 23:50:56	announced

Dataset with its publication pending

submitter keyword: Ag85B-Fc2a, transcriptome, proteome analysis

Qiaofeng Wan
contact affiliation	Ningxia Medical University
contact email	wqiaofeng@126.com
lab head
Tiansong Wang
contact affiliation	Ningxia Medical University
contact email	shanyanghaoranqi@126.com
dataset submitter

iProX dataset URI