PXD052745-1

PXD052745 is an original dataset announced via ProteomeXchange.

Title	Collaboration of PARP family members in non-cancer disease mechanism
Description	Our work can be summarized as the establishment of protein-binding database for PARPs family as well as a comprehensive multi-omics analysis to show its potential for pathogenic mechanism study of the PARPs family. We concluded that the pathogenic role of PARPs family extends far more than cancer. Besides potential roles in neuron-degeneration diseases, results from multiple independent bio-informatic analysis indicate several PARP family members may involve in diabetes’ complication and closely related disease like types of hypertension and Systemic lupus erythematosus. The relationship between PARPs and diabetes are supported in recent reports.
HostingRepository	PRIDE
AnnounceDate	2024-07-15
AnnouncementXML	Submission_2024-07-14_19:38:08.847.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zheng Jeff
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	biotinylated residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-30 23:07:52	ID requested
⏵ 1	2024-07-14 19:38:09	announced
2	2024-10-22 06:49:45	announced	2024-10-22: Updated project metadata.
3	2024-11-25 06:00:00	announced	2024-11-25: Updated project metadata.

Dataset with its publication pending

submitter keyword: Human,Interactome,PARP,TurboID

Zheng Jiefu
contact affiliation	Department of Clinical Laboratory, Shenshan Central Hospital, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Shanwei, China
contact email	zhengjf25@mail3.sysu.edu.cn
lab head
Zheng Jeff
contact affiliation	Sun Yat-sen University
contact email	zhengjf25@mail3.sysu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD052745

PRIDE project URI

• PRIDE
  1. PXD052745
     1. Label: PRIDE project
     2. Name: Collaboration of PARP family members in non-cancer disease mechanism