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PXD052716-1

PXD052716 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMitigating in-column artificial modification in HTLC for bottom-up proteomics and quality control of biopharmaceuticals
DescriptionThe study aimed to investigate the effect of an additional short trap column installed upstream of the separation column on the in-column artificial modification and separation performance in high-temperature LC-MS analyses of peptides.
HostingRepositoryPRIDE
AnnounceDate2024-09-11
AnnouncementXMLSubmission_2024-09-11_06:21:01.288.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJuraj Lenco
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606; scientific name: Francisella tularensis subsp. holarctica (strain LVS); NCBI TaxID: 376619;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-30 07:19:36ID requested
12024-09-11 06:21:02announced
Publication List
Starovoit MR, Jadeja S, Gaz, á, rkov, á T, Len, č, o J, Mitigating In-Column Artificial Modifications in High-Temperature LC-MS for Bottom-Up Proteomics and Quality Control of Protein Biopharmaceuticals. Anal Chem, 96(36):14531-14540(2024) [pubmed]
10.1021/acs.analchem.4c02819;
Keyword List
submitter keyword: biopharmaceuticals, high-temperature liquid chromatography, column temperature, trap column,bottom-up proteomics, artifacts
Contact List
Dr Juraj
contact affiliationCharles University, Faculty of Pharmacy in Hradec Králové,Department of Analytical Chemistry, Akademika Heyrovského 1203/8 500 05 Hradec Králové, Czech Republic
contact emaillenco@faf.cuni.cz
lab head
Juraj Lenco
contact affiliationFaculty of Pharmacy, Charles University
contact emaillenco@faf.cuni.cz
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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