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PXD052657-2

PXD052657 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
DescriptionMatrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) data investigating changes in extracellular matrix/collagen architecture of mouse tumor tissue in response to LOX inhibition. Sample Key: Vehicle, Doxo (Chemotherapy drug), 6403 (LOX inhibitor), Combo (Doxo + LOX inhibitor)
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_06:51:10.188.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterPeggi Angel
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListacetylated residue; monohydroxylated residue; deamidated residue
InstrumentBruker Daltonics instrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02024-05-29 00:52:51ID requested
12024-07-25 09:33:56announced
22024-10-22 06:51:10announced2024-10-22: Updated project metadata.
Publication List
10.1016/J.CHEMBIOL.2024.06.012;
Keyword List
submitter keyword: LOX inhibitor, Mouse,Lysyl oxidase, TNBC chemoresistance
Contact List
Harrison Taylor
contact affiliationPharmacology Department; Angel Lab; Medical University of South Carolina; United States of America
contact emailtaylorha@musc.edu
lab head
Peggi Angel
contact affiliationMedical University of South Carolina
contact emailangelp@musc.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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