PXD052564 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Nucleotide metabolism-related host proteins RPB2 and UPP1 interacting with PEDV N proteins affect viral replication |
| Description | Porcine epidemic diarrhea virus (PEDV) is a highly pathogenic infectious disease targeting pig intestine that is widespread in the world, causing huge economic losses to pig industry. PEDV N protein is the core protein of PEDV, which locates in the cytoplasm and wraps the RNA genome of the virus to form spiral ribonucleoprotein (RNP). However, host proteins interacting with N proteins and their role in PEDV replication have not been fully elucidated. In this study, PEDV-N labeled antibodies were immunoprecipitated (Co-IP) and combined with LC-MS/MS to screen host proteins interacting with N proteins. |
| HostingRepository | PRIDE |
| AnnounceDate | 2024-06-07 |
| AnnouncementXML | Submission_2024-06-07_03:47:54.858.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Qiyuan Kuang |
| SpeciesList | scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF; Thermo Fisher Scientific instrument model |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-05-25 23:10:47 | ID requested | |
| ⏵ 1 | 2024-06-07 03:47:55 | announced | |
| 2 | 2024-10-22 06:44:00 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
| submitter keyword: Protein interaction,Porcine epidemic diarrhea virus, N protein, UPP1, RPB2 |
Contact List
| Guihong Zhang |
|---|
| contact affiliation | South China Agricultural University |
| contact email | guihongzh@scau.edu.cn |
| lab head | |
| Qiyuan Kuang |
|---|
| contact affiliation | South China Agricultural University |
| contact email | 20222028015@stu.scau.edu.cn |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052564
- Label: PRIDE project
- Name: Nucleotide metabolism-related host proteins RPB2 and UPP1 interacting with PEDV N proteins affect viral replication
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