PXD052497 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of ASC-interacting proteins |
Description | To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that interacted with ASC. We compared the IP products between WT BMDMs and Asc–/– BMDMs, and found that many proteins specifically interacted with ASC. |
HostingRepository | PRIDE |
AnnounceDate | 2024-05-29 |
AnnouncementXML | Submission_2024-05-28_17:45:30.603.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Xiaopeng Qi |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2024-05-22 20:20:38 | ID requested | |
⏵ 1 | 2024-05-28 17:45:31 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: ASC, Francisella novicida, inflammasome, BMDM, mouse |
Contact List
Xiaopeng Qi |
contact affiliation | Key Laboratory for Experimental Teratology of the Ministry of Education, Advanced Medical Research Institute, Qilu Hospital, Cheeloo College of Medicine, Shandong University |
contact email | xqi@email.sdu.edu.cn |
lab head | |
Xiaopeng Qi |
contact affiliation | Key Laboratory for Experimental Teratology of the Ministry of Education, Department of Clinical Laboratory/Qilu Hospital, Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University |
contact email | xqi@email.sdu.edu.cn |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/05/PXD052497 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052497
- Label: PRIDE project
- Name: Identification of ASC-interacting proteins