PXD052368-1

PXD052368 is an original dataset announced via ProteomeXchange.

Title	The extracellular matrix (ECM) and integrin adhesion complexes (IACs) composition in DU145 prostate cancer parental and radioresistant cells
Description	Cell adhesion to the extracellular matrix (ECM) is a critical component of malignant transformation, cancer progression, and the development of radioresistance. This mechanism of cancer cell resistance to therapy is defined as the cell adhesion mediated radioresistance (CAM-RR). There are two groups of proteins whose alteration can lead to the emergence of CAM-RR: (i) adhesion molecules (collectively called adhesome) and (ii) ECM molecules (collectively called matrisome). In order to identify proteins that mediate radioresistance, in this study we analyzed the adhesomes and matrisomes of DU145 parental and radioresistant prostate cancer cells.
HostingRepository	PRIDE
AnnounceDate	2024-07-31
AnnouncementXML	Submission_2024-07-31_09:59:59.740.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ivana Samarzija
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-05-18 15:38:16	ID requested
⏵ 1	2024-07-31 10:00:00	announced

10.3389/FCELL.2024.1452463;

submitter keyword: integrin adhesion complexes (IACs), radioresistance,Prostate cancer, extracellular matrix

Andreja Ambriovic Ristov
contact affiliation	Laboratory for Cell Biology and Signalling, Rudjer Boskovic Institute, Zagreb, Croatia
contact email	andreja.ambriovic.ristov@irb.hr
lab head
Ivana Samarzija
contact affiliation	Rudjer Boskovic Institute, Zagreb
contact email	ivana.samarzija@irb.hr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/07/PXD052368

PRIDE project URI

• PRIDE
  1. PXD052368
     1. Label: PRIDE project
     2. Name: The extracellular matrix (ECM) and integrin adhesion complexes (IACs) composition in DU145 prostate cancer parental and radioresistant cells