PXD052167 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia |
| Description | Myopia is a growing global public health concern. The retinal–choroid–sclera (RCS) signalling cascade is crucial in regulating eye growth and is influenced by visually induced signalling. Understanding the molecular mechanisms underlying this cascade is vital to identify therapeutic targets for myopia. This study provides an in-depth proteomic and phosphoproteomic atlas of the RCS in guinea pigs with FDM, uncovering the potential molecular mechanisms driving the progression of myopia. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-17 |
| AnnouncementXML | Submission_2025-11-16_16:35:38.100.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yifan Song |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | phosphorylated residue |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-05-10 00:13:08 | ID requested | |
| ⏵ 1 | 2025-11-16 16:35:39 | announced | |
Publication List
| 10.1016/j.mcpro.2025.101069; |
| Song Y, Xu Z, Li HT, Xie Y, Zhao L, Feng J, Luo A, Dai J, Li J, Guo X, Song J, Bi H, Proteomic and Phosphoproteomic Characteristics of the Retina, Choroid, and Sclera in Guinea Pigs with Form-Deprivation Myopia. Mol Cell Proteomics, 24(11):101069(2025) [pubmed] |
Keyword List
| submitter keyword: phosphoproteomic,Proteomic, form-deprivation myopia (FDM) |
| retina-choroid-sclera (RCS) |
Contact List
| Hongsheng Bi |
|---|
| contact affiliation | Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine |
| contact email | hongshengbi1@163.com |
| lab head | |
| Yifan Song |
|---|
| contact affiliation | Shandong University of Traditional Chinese Medicine |
| contact email | songyifan0505@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD052167 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD052167
- Label: PRIDE project
- Name: Proteomic and phosphoproteomic study in the retina, choroid, and sclera of guinea pigs with form-deprivation myopia
