PXD051893-1

PXD051893 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomics of iPSC-RPE from human donors
Description	In the project “Quantitative proteomics of iPSC-RPE from human donors” label-free quantitative expression proteomics of iPSC-RPE cells derived from the conjunctiva of human donors was performed. Cells were differentiated using standard protocols (PMID: 33292045) and treated for 24 hours with either vehicle (DMSO, Ctrl), 10 uM CA77.1, or 20 mM NH4Cl + 100 uM Leupeptin (N/L), to assess the effect of autophagy modulation on proteome remodeling.
HostingRepository	PRIDE
AnnounceDate	2025-10-06
AnnouncementXML	Submission_2025-10-06_12:22:02.996.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joern Dengjel
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-30 09:00:07	ID requested
⏵ 1	2025-10-06 12:22:03	announced

Dataset with its publication pending

submitter keyword: Human, autophagy, iPSC, retina, LC-MS/MS

Joern Dengjel
contact affiliation	Department of Biology, University of Fribourg Chemin du Musée 10, 1700 Fribourg, Switzerland T +41 26 300 8631
contact email	joern.dengjel@unifr.ch
lab head
Joern Dengjel
contact affiliation	University of Fribourg
contact email	joern.dengjel@medizin.uni-freiburg.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/10/PXD051893

PRIDE project URI

• PRIDE
  1. PXD051893
     1. Label: PRIDE project
     2. Name: Quantitative proteomics of iPSC-RPE from human donors