PXD051863-1

PXD051863 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	isoAsp analysis of bovine lens alpha-crystallin
Description	Isomerization of Asp residues has been long thought to occur only in a few tissues. Recent reports suggested that such post-translational protein modifications may occur in all tissues and proteins in vivo, including serum. For proof of concept using comprehensive analysis, the MS-based proteomic approach is straightforward; however, the isomerization of Asp has not been involved in proteomics studies because of no change in molecular weight. Here, we show a novel strategy, isoAsp-Quest, a database search-oriented large-scale isoAsp identification method.
HostingRepository	jPOST
AnnounceDate	2025-04-30
AnnouncementXML	Submission_2025-04-29_08:00:16.855.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hiroaki Sakaue
SpeciesList	scientific name: Bos taurus; NCBI TaxID: 9913;
ModificationList	S-carboxamidomethyl-L-cysteine; Ammonia-loss; 2-pyrrolidone-5-carboxylic acid (Gln); L-methionine sulfoxide; Delta:H(-1)N(-1)18O(1); unknown modification
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-29 15:06:43	ID requested
⏵ 1	2025-04-29 08:00:17	announced

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: isoAsp, isomerization

submitter keyword: isoAsp, isomerization

Contact List

Hiroaki Sakaue
lab head
Hiroaki Sakaue
contact affiliation	National Institute of Advanced Industrial Science and Technology (AIST)
dataset submitter

Full Dataset Link List

jPOST dataset URI
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jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST003061/