PXD051789-1

PXD051789 is an original dataset announced via ProteomeXchange.

Title	Total proteomic analysis of peripheral blood mononuclear cells from oral squamous cell carcinoma patients using DIA-MS approach
Description	The present study explores DIA-MS method to identify potential protein targets in peripheral blood mononuclear cells (PBMC) of oral squamous cell carcinoma patients in a cancer-control cohort. The total proteomic analysis has identified about 3139 proteins among which 449 proteins showed altered expression in OSCC group compared to the control. Within the subset of the differentially expressed proteins, several potential protein candidates were identified with immunomodulatory activities that are favorable towards the cancer progession and survival. Further researach can be carried out to validate and utilize these protein targets in the clinical settings.
HostingRepository	PRIDE
AnnounceDate	2024-08-22
AnnouncementXML	Submission_2024-08-22_06:05:13.329.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Keshava Prasad T. S.
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-26 23:32:10	ID requested
⏵ 1	2024-08-22 06:05:13	announced
2	2024-10-22 06:55:27	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: Data-independent acquisition, Oral cancer,Immune cells

Dr. T. S. Keshava Prasad
contact affiliation	Professor and Deputy Director Center for Systems Biology and Molecular Medicine Yenepoya Research Centre Yenepoya (Deemed to be University)
contact email	tskprasad@gmail.com
lab head
Keshava Prasad T. S.
contact affiliation	Institute of Bioinformatics, Bangalore, Karnataka, India.
contact email	keshav@ibioinformatics.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2024/08/PXD051789

PRIDE project URI

• PRIDE
  1. PXD051789
     1. Label: PRIDE project
     2. Name: Total proteomic analysis of peripheral blood mononuclear cells from oral squamous cell carcinoma patients using DIA-MS approach