PXD051673-1

PXD051673 is an original dataset announced via ProteomeXchange.

Title	Huamn iPSC midbrain neuron Parkinson disease
Description	Proteomic analysis of iPSC-midbrain neuron cultures from Parkinson's disease patients haboring A53T pathogenic variant
HostingRepository	PRIDE
AnnounceDate	2025-08-25
AnnouncementXML	Submission_2025-08-24_16:20:25.430.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Joseph Mazzulli
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-23 11:42:11	ID requested
⏵ 1	2025-08-24 16:20:26	announced

10.1016/j.neuron.2024.05.003;

Belur NR, Bustos BI, Lubbe SJ, Mazzulli JR, Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson's disease and dementia with Lewy bodies. Neuron, 112(15):2558-2580.e13(2024) [pubmed]

submitter keyword: synuclein, midbrain,iPSC, Parkinsons disease

Joseph Mazzulli
contact affiliation	Northwestern University Feinberg School of Medicine
contact email	jmazzulli@northwestern.edu
lab head
Joseph Mazzulli
contact affiliation	Northwestern University
contact email	jmazzulli@northwestern.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/08/PXD051673

PRIDE project URI

• PRIDE
  1. PXD051673
     1. Label: PRIDE project
     2. Name: Huamn iPSC midbrain neuron Parkinson disease