PXD051296-1

PXD051296 is an original dataset announced via ProteomeXchange.

Title	Products differentially secreted from perigonadal adipose tissue of overfed mice.
Description	Male C57BL/6J mice were implanted with intragastric catheters that allowed direct infusion of liquid into the stomach. A control group of mice received saline through the catheter and was given free access to high-fat diet (Research Diets D12492i, 60% calories from fat) over a span of months, leading to “ad libitum obesity” (ALO). Another group of mice received a hypercaloric liquid diet through the catheter, leading to an acute-onset, “overfeeding-induced obesity” (OIO). OIO mice were also given free access to high-fat diet but did not consume it while receiving hypercaloric intragastric infusions. After 12 days of infusions, the average weights of the two groups were equal. All mice were fasted for 24 hours, after which they were sacrificed and perigonadal adipose tissue (PGAT) was dissected out. PGAT was cultured ex vivo for 6 hours, after which conditioned media was collected and submitted for proteomic profiling. All mice were age-matched and 16 weeks old at time of sacrifice. “HFD” is also used to refer to the ALO condition, while “OID” is also used to refer to the OIO condition.
HostingRepository	PRIDE
AnnounceDate	2025-02-20
AnnouncementXML	Submission_2025-02-20_06:44:49.938.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rajesh Soni
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	time-of-flight

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-09 02:29:50	ID requested
⏵ 1	2025-02-20 06:44:50	announced

Dataset with its publication pending

submitter keyword: Adipose Tissue,Mouse, Overfeeding

Anthony Ferrante Jr.
contact affiliation	Tilden-Weger-Bieler Professor of Medicine Chief of Preventive Medicine & Nutrition Columbia University
contact email	awf7@cumc.columbia.edu
lab head
Rajesh Soni
contact affiliation	Columbia University Medical center
contact email	rs3869@cumc.columbia.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/02/PXD051296

PRIDE project URI

• PRIDE
  1. PXD051296
     1. Label: PRIDE project
     2. Name: Products differentially secreted from perigonadal adipose tissue of overfed mice.