PXD051268-1

PXD051268 is an original dataset announced via ProteomeXchange.

Title	FBL knockdown effects on proteome
Description	We measured the impact of knocking down FBL on the proteome of Homo sapiens.
HostingRepository	PRIDE
AnnounceDate	2025-11-28
AnnouncementXML	Submission_2025-11-28_04:47:40.021.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	André Mateus
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-08 02:40:08	ID requested
⏵ 1	2025-11-28 04:47:41	announced

10.1016/j.canlet.2025.218124;

Groza P, Kumari K, Esteva-Socias M, Schott J, Bhattarai DP, Sajkowska JJ, Dasgupta R, Peula C, Destefanis E, Williams C, Marchand V, Wikstr, ö, m P, Wiberg R, Campos AB, Gilthorpe JD, Pop B, Mateus A, Motorin Y, Dassi E, Petzold K, Tuorto F, Aguilo F, Fibrillarin-dependent 2'-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation. Cancer Lett, 639():218124(2026) [pubmed]

submitter keyword: FBL, knockdown, human

Francesca Aguilo
contact affiliation	Umea University
contact email	francesca.aguilo@umu.se
lab head
André Mateus
contact affiliation	Umeå University
contact email	andre.mateus@umu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD051268

PRIDE project URI

• PRIDE
  1. PXD051268
     1. Label: PRIDE project
     2. Name: FBL knockdown effects on proteome