PXD051242-1

PXD051242 is an original dataset announced via ProteomeXchange.

Title	DIA proteomics analysis of mice in models of myocardial infarction and heart failure with preserved ejection fraction (HFpEF).
Description	The dataset includes two parts: a) Proteomics of mouse heart tissue 14 days after myocardial infarction and long-term exercised mice post-myocardial infarction for 14 days; b) Cardiac proteomics of a model of heart failure with preserved ejection fraction (HFpEF) induced by L-NAME and high-fat diet-fed wild-type mice, as well as adeno-associated virus-mediated FGF21 overexpression mice and control groups.
HostingRepository	iProX
AnnounceDate	2024-04-05
AnnouncementXML	Submission_2026-09-07_00:33:36.842.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei Xie
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2024-04-06 20:45:40	ID requested
⏵ 1	2026-09-07 00:33:38	announced

Zhang K, Gan J, Wang B, Lei W, Zhen D, Yang J, Wang N, Wen C, Gao X, Li X, Xu A, Liu X, Li Y, Wu F, Lin Z, FGF21 protects against HFpEF by improving cardiac mitochondrial bioenergetics in mice. Nat Commun, 16(1):1661(2025) [pubmed]

Xie W, Gan J, Zhou X, Tian H, Pan X, Liu W, Li X, Du J, Xu A, Zheng M, Wu F, Li Y, Lin Z, Myocardial infarction accelerates the progression of MASH by triggering immunoinflammatory response and induction of periosti. Cell Metab, 36(6):1269-1286.e9(2024) [pubmed]

submitter keyword: DIA, MI, HFpEF, Heart

Zhuofeng Lin
contact affiliation	Wenzhou Medical University
contact email	zhuofenglin@wmu.edu.cn
lab head
Wei Xie
contact affiliation	Wenzhou Medical University
contact email	xiewei06@126.com
dataset submitter

iProX dataset URI