PXD051236 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Placenta-derived Extracellular Vesicles in Maternal Plasma of Hb Bart’s Fetuses |
| Description | Our study has demonstrated a profile of extracellular vesicle (EVs) in women with Hb Bart’s fetalis fetuses. Specifically, women with Bart’s fetuses have smaller EVs particle size but higher placental alkaline phosphatase (PLAP)-EV level than those with normal pregnancies. Several proteomics EV proteins are differentially expressed in women with Bart’s fetuses and these proteins involves in zymogen activation, fibrinogen complex, vesicles in cellular component, fibrin clot formation and integrin signaling. We envision that the non-invasive liquid biopsy could provide information in relation to placental health in women with Bart’s fetuses. In this report, the liquid biopsy based on an examination of placenta-derived EVs in maternal blood for the identification of Hb Bart’s fetuses is feasible and this may ultimately reduce the rate of unnecessary invasive prenatal diagnosis testing inthe future. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-12-03 |
| AnnouncementXML | Submission_2025-12-03_13:59:18.020.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | PUNTABUT WARINTAKSA |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2024-04-06 13:58:06 | ID requested | |
| ⏵ 1 | 2025-12-03 13:59:19 | announced | |
Publication List
| 10.1038/s41598-025-24900-0; |
| Chaemsaithong P, Warintaksa P, Ruangvutilert P, Luewan S, Phatihattakorn C, Raungrongmorakot K, Chaiyasit N, Tachjaree TP, Prakobpanich M, Panachan J, Kunsawat T, Chiangjong W, Chutipongtanate S, Placenta-derived extracellular vesicles in maternal plasma of Hb Bart's fetuses. Sci Rep, 15(1):41140(2025) [pubmed] |
Keyword List
| submitter keyword: exosomes, extracellular vesicle, proteomics, placenta-derived exosome, hydrops fetalis,Bart |
Contact List
| Dr Wararat Chiangjong |
|---|
| contact affiliation | Pediatric Translational Research Unit, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand |
| contact email | wararat_01@yahoo.com |
| lab head | |
| PUNTABUT WARINTAKSA |
|---|
| contact affiliation | Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand |
| contact email | puntabut.war@mahidol.ac.th |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/12/PXD051236 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD051236
- Label: PRIDE project
- Name: Placenta-derived Extracellular Vesicles in Maternal Plasma of Hb Bart’s Fetuses
