PXD051116-2

PXD051116 is an original dataset announced via ProteomeXchange.

Title	Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome clustered regularly interspaced short palindromic repeats interference library
Description	In this study, a whole-genome CRISPRi library was developed in Y. lipolytica and applied for enforcing the tolerance to furfural and acetic acid. Several novel gene targets were discovered through NGS before and after screening. And to analyze the tolerance mechanism caused by transcriptional repression of the most prominent gene targets, the transcriptome and proteomics were performed.
HostingRepository	iProX
AnnounceDate	2024-03-31
AnnouncementXML	Submission_2024-10-11_23:44:31.303.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Qianxi He
SpeciesList	scientific name: Yarrowia lipolytica; NCBI TaxID: 4952;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ

Revision	Datetime	Status	ChangeLog Entry
0	2024-03-31 20:03:09	ID requested
1	2024-03-31 20:03:31	announced
⏵ 2	2024-10-11 23:44:32	announced	2024-10-12: Update information.

Fang L, Chen Y, He Q, Wang L, Duan Q, Huang C, Song H, Cao Y, Mining novel gene targets for improving tolerance to furfural and acetic acid in Yarrowia lipolytica using whole-genome CRISPRi library. Bioresour Technol, 403():130764(2024) [pubmed]

submitter keyword: CRISPRi library, yarrowia lipolytica, furfural tolerance, acetic tolerance

Yingxiu Cao
contact affiliation	Tianjin University
contact email	caoyingxiu@tju.edu.cn
lab head
Qianxi He
contact affiliation	Tianjin University
contact email	a18080502576@outlook.com
dataset submitter

iProX dataset URI