PXD050942-1
PXD050942 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SUMOylation-Induced Membrane Localization of TRPV1 Suppresses Proliferation and Migration in Gastric Cancer Cells |
| Description | In this work, we elucidate a novel mechanism wherein TRPV1 SUMOylation promotes its membrane expression and activates the TRPV1-Ca2+-AMPK signaling pathway, thereby inhibiting GC cell proliferation and migration. These findings enhance our understanding of the molecular dynamics in gastric cancer and could provide a new theoretical basis for clinical treatment strategies. |
| HostingRepository | iProX |
| AnnounceDate | 2024-03-25 |
| AnnouncementXML | Submission_2025-06-29_21:11:30.486.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yang Yang |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive Plus; Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2024-03-24 22:46:57 | ID requested | |
| ⏵ 1 | 2025-06-29 21:11:30 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: GC, TRPV1, SUMOylation, Membrane expression, AP2M1, AMPK |
Contact List
| Yang Yang | |
|---|---|
| contact affiliation | Shanghai Jiao Tong University |
| contact email | princess_yanggirl@alumni.sjtu.edu.cn |
| lab head | |
| Yang Yang | |
| contact affiliation | Shanghai Jiao Tong University |
| contact email | princess_yanggirl@alumni.sjtu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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